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pentobarbital will reduce the extent or outcome of cinacalcet by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.pentobarbital will lower the level or effect of roflumilast by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration not advised; solid cytochrome P450 enzyme inducers reduce sy